Biosafety Science and Policy
Instructors: Dr. Anne Kapuscinski and Dr. Emily Pullins
NRES 5482 (3 cr.), Registration #64597
Thursdays, 5:10-6:45 p.m.

19 Green Hall, St. Paul Campus

Classes
This course will be taught through a series of lectures, guest speakers, discussions, and student activities.  Class will meet two days per week (one for presentations and lectures and one for discussion section), 1.5 hr. each session. 

Introduction
Scientists and regulators are now developing methods to ensure the equitable and safe use of biological technologies, such as genetic engineering and cloning, and their products, such as growth-enhanced, transgenic fish. One of the most important new analytical approaches to assessment and management of these new technologies is the burgeoning field of biosafety science. Using a combination of methods such as risk assessment, risk management, safety engineering and formal deliberative techniques, biosafety science will provide sound science approaches in the use of new biological technologies.

Along with biosafety science, we will explore the innovations in safety policy that may be necessary for appropriate management and use of biotechnologies. How, we ask, can biotechnological science and its products develop can be openly examined and managed for safety by independent scientists, governments, industry, and concerned citizens? We will explore existing policy programs, national and international, that govern the use of biological technologies currently, and then explore how a focus on safety may result in changes to existing policies.

Objectives
By the end of the course the student will be able to:

  • develop and utilize biosafety science approaches for use in the analytical assessment of new biological technologies;
  • access and understand diverse perspectives on biosafety policy,
  • critically analyze environment and human health safety issues relating to genetic engineering and other biotechnologies using a multi-disciplinary perspective,
  • engage their communities in in-depth discussions about biosafety, and
  • develop and submit an original piece to a peer-reviewed academic journal.

Student Activities
The student will participate in the following activities during the course:

  • Participate in class discussions
  • Read and discuss scientific papers and other assigned reading
  • Write and present a 3-5 page individual paper
  • Write and present a group paper suitable for publication

Individual Paper and Presentation
The individual paper is due during the sixth week of class; it is a 3-5 page essay, and can be written from the disciplinary perspective of the student.  This paper can be a literature review on a topic related to genetic engineering or an analysis of some aspect of a genetically modified organism.  The intention of this assignment is to introduce students to the topic of genetic engineering, and to make clear the links between their discipline and genetic engineering.  All students will present their papers to the class during lecture, and this will introduce students to the breadth of the interdisciplinary nature of genetic engineering.

Group Paper and Presentation
The group paper is a critique of the current governance of biotechnology and recommendations for improvement.  The paper should highlight interdisciplinary links and integrate material from the course, readings, and an independent literature search.  The topics for the paper should be decided upon by the fourth week of class, and rough drafts are due on the twelfth week of class.  The format of the paper should conform to the writer’s guidelines for a peer-reviewed academic journal of the group’s choosing.  Groups must turn in a copy of the journal’s writers’ guidelines when they turn in the paper.  The rough draft will undergo peer editing by students, then will receive comments by the professors, and the final paper will be due on the last week of class.  The paper will be presented in the format of an oral presentation during finals week.

Class assignments
A variety of assignments will be required throughout the course.  These include editing your peers’ paper rough drafts, completing a worksheet from the Biosafety Manual, short essays on a variety of topics, preliminary assignments in support of the paper, and other assignments that will be announced in class.  Consult the course schedule and instructors for details on how to turn in these assignments; some will be posted to the website while others will be due at the beginning of class. More details about how course assignments will be graded are provided in the handouts to be distributed during class.

A note about group projects
Group projects are an excellent way to learn from your classmates.  Individual grades must be granted for these projects, however.  To help resolve this problem, several assignments related to the group project will receive individual grades.  Also, at the end of the project, we will ask every student will be asked to turn in a written description of your contribution to the project and that of the other members of the group. The instructors will take this information into consideration in assigning an appropriate grade to each member of the group.

Grading


This course is offered on an A-F or Pass-Fail basis.  Grading will be based on the following components:

  • Class attendance and participation             10%
  • Class assignments 6 x 5%                         30%
  • Individual paper assignment                       5%
  • Final individual paper                                 10%
  • Individual paper presentation                      5%
  • Group paper assignments 2 x 5%                10%
  • Final group paper                                       20%
  • Group paper presentation                            10%

If you are having difficulty in this course, we encourage you to consult the Instructors or TA during office hours, or set up an appointment.  Please come to us sooner rather than later.

Materials
Reading materials required for this class include:

  • Genetically Engineered Organisms: Assessing Environmental and Human Health Effects, by D.K. Letourneau and B.E. Burrows, Eds., CRC Press, 2001.
  • Understanding Risk, by Stern and Fineberg, Eds., National Academy Press, 1997. 
  • Two course packets - one main reader and one discussion reader

Subject Material
Note that this course deals with some issues that are controversial.  We consider discussion of such differences of opinion to be healthy.  However, we expect this discussion to be respectful and also expect all students to cooperate fully on group projects with their peers regardless of differences.

Academic Misconduct
Academic misconduct is defined in the University of Minnesota policy as "the fabrication or falsification of data, research procedures, or data analysis; destruction of data for fraudulent purposes; plagiarism; abuse of confidentiality; or other fraudulent actions in proposing, conducting, reporting, or reviewing research or other scholarly activity."  Such misconduct will not be tolerated in this course.  Students may refer to university policy or consult the Instructors for further clarification on this subject.

Accessibility
It is University policy to provide, on a flexible and individualized basis, reasonable accommodations to students who have disabilities that may affect their ability to participate in course activities or to meet course requirements. Students with disabilities are encouraged to contact their instructors or TAs early in the semester to discuss their individual needs for accommodations.

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