Gerald Ankley

Goldy Gopher
Adjunct Associate Professor
[email protected]
Education

Ph.D. University of Georgia

External Affiliations

Environmental Protection Agency

Areas of Interest

Ecotoxicology

Research

My research focuses on the effects of chemicals with differing toxic mechanisms on the long-term health of aquatic animals, primarily fish. Current efforts involve a class of toxicants broadly labeled endocrine-disrupting chemicals (EDCs) that cause a wide range of adverse effects on development and reproduction that can lead to substantial population-level impacts. This research involves conventional toxicology approaches (e.g., whole animal tests) used in conjuntion with state-of-the-art genomic, bioinformatic and computational tools.

Select Publications

  • Perkins, E.J., N. Garcia-Reyero, D.L. Villeneuve, D. Martinovic, S.M. Brasfield, L.S. Blake, J.D. Brodin, N.D. Denslow and G.T. Ankley.  2008.  Perturbation of gene expression and steroidogenesis with in vitro exposure of fathead minnow ovaries to ketoconazole. Mar. Environ. Res. In press.
  • Villeneuve, D.L., I. Knoebl, P. Larkin, A.L. Miracle, B.J. Carter, N.D. Denslow and G.T. Ankley.  2008.  Altered gene expression in the brain and liver of female fathead minnows exposed to fadrozole.  J. Fish Biol. In press.
  • Villeneuve, D.L., L.S. Blake, J.D. Brodin, J.E. Cavallin, E.J. Durhan, K.M. Jensen, M.D. Kahl, E.A. Makynen, C. Martinovic. N.D. Mueller and G.T. Ankley.  2008.  Effects of a 3β-hydroxysteroid dehydrogenase inhibitor, trilostane, on the fathead minnow reproductive axis.  Toxicol. Sci. In press.
  • Wang, R.-L., D. Bencic, A. Biales, D. Lattier, M. Kostich, D. Villeneuve, G.T. Ankley, J. Lazorchak and G. Toth.  2008.  DNA microarray-based ecotoxicological discovery in a small fish species.  Environ. Toxicol. Chem. 27, 664-675.
  • Wang, R.-L., A. Biales, D. Bencic, D. Lattier, M. Kostich, D. Villeneuve, G.T. Ankley, J. Lazorchak and G. Toth.  2008.  DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors impacting transcriptional profiles in a small fish species.  Environ. Toxicol. Chem. 27, 652-663.